The impact of delaying enteral feeding on gastric emptying, plasma cholecystokinin, and peptide YY concentrations in critically ill patients

What Was Tested

Researchers studied Peptide YY and Cholecystokinin (CCK) in this randomized controlled trial publication.

This study examined the impact of delayed feeding on GE, plasma CCK, and peptide YY (PYY) concentrations in the critically ill.

Who Took Part

The age groups tagged for this paper are middle-aged adults, both men and women.

Twenty-eight critically ill patients were randomized to receive EN either within 24 hrs of admission ("early feeding": 54.9 +/- 3.3 yrs; Acute Physiology and Chronic Health Evaluation (APACHE) II = 23.0 +/- 1.8) or on day 4 of admission after GE assessment ("delayed feeding": 56.1 +/- 4.2 yrs, APACHE II = 21.7 +/- 1.8).

Blood was sampled for measurement of plasma CCK, PYY, and glucose concentrations.

How the Study Was Run

The researchers set it up as a randomized study.

Because people in this Peptide YY study were split into groups at random, differences between the groups are less likely to reflect who happened to join each one.

Mixed medical and surgical intensive care unit (ICU).

What Was Measured

The subject headings attached to it are Cholecystokinin, Critical Illness, Enteral Nutrition, Gastric Emptying and Peptide YY.

What This Means in Plain Language

The paper is a randomized study of Peptide YY and Cholecystokinin (CCK).

The abstract goes on to report its results in about 7 sentences; this page does not restate them, so read the paper for the findings and their limits.

The publication is from 2008 (Critical care medicine), a journal based in United States.

More context: the Peptide YY compound page and the Cholecystokinin (CCK) compound page, all human trials.