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Effect of a pre-exercise energy supplement on the acute hormonal response to resistance exercise.
Plain-language guide to PMID 18438227 (2008): double-blind randomized controlled trial of Caffeine and Creatine.
Key Facts
- PMID
- 18438227
- Journal
- Journal of strength and conditioning research
- Year
- 2008
- Study type
- Randomized Controlled Trial
- Authors
- Hoffman JR et al. (6 authors)
- DOI
- 10.1519/JSC.0b013e31816d5db6
What This Study Did, in Plain Language
What Was Tested
Researchers studied Caffeine and Creatine in this randomized controlled trial publication.
The effect of a pre-exercise energy sport drink on the acute hormonal response to resistance exercise was examined in eight experienced resistance trained men.
Subjects were randomly provided either a placebo (P: maltodextrin) or the supplement (S: combination of branched chain amino acids, creatine, taurine, caffeine, and glucuronolactone).
Who Took Part
The age groups tagged for this paper are adults, men only.
How the Study Was Run
The design is described as randomized, double-blind, placebo-controlled and crossover.
Random assignment meant chance, not the researchers, decided who got Caffeine and who got the comparison, which limits bias.
Neither the participants nor the staff measuring them knew who was on Caffeine, so expectations could not easily colour the readings.
A placebo (an inactive look-alike) gave the Caffeine group a baseline to be compared against.
Each person switched between Caffeine and the comparison at some point, usually with a gap in between.
What Was Measured
Blood draws occurred at baseline pre-exercise, immediately post- (IP), 15 minutes post- (15P), and 30-minutes post (30P) exercise for measurement of serum growth hormone, total and free testosterone, cortisol, and insulin concentrations.
The subject headings attached to it are Amino Acids, Essential, Analysis of Variance, Area Under Curve, Blood Chemical Analysis, Caffeine, Creatine and Dietary Supplements.
What This Means in Plain Language
The paper is a randomized, double-blind and placebo-controlled study of Caffeine and Creatine.
The publication is from 2008 (Journal of strength and conditioning research), a journal based in United States.
More context: all human trials.
Related Pages
Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.