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Efficacy and safety of growth hormone treatment in children born small for gestational age in Japan.

Plain-language guide to PMID 18655523 (2008): open-label randomized controlled trial of Exogenous HGH, sermorelin & older GHRPs (why they're passed over) in 34 patients.

Key Facts

PMID
18655523
Journal
Journal of pediatric endocrinology & metabolism : JPEM
Year
2008
Study type
Randomized Controlled Trial
Authors
Tanaka T et al. (6 authors)
DOI
10.1515/jpem.2008.21.5.423

What This Study Did, in Plain Language

What Was Tested

This randomized controlled trial looks at Exogenous HGH, sermorelin & older GHRPs (why they're passed over).

Who Took Part

The abstract describes 34 patients taking part.

PubMed indexes the participants as young children and children, both men and women.

Growth-promoting effects and safety of growth hormone (GH) treatment in prepubertal short-statured children born small for gestational age (SGA) were evaluated in a multicenter, open-label, randomized parallel-group comparison study.

How the Study Was Run

The researchers set it up as a randomized, open-label, multicenter and parallel-group study.

The patients were allocated by chance, so the Exogenous HGH, sermorelin & older GHRPs (why they're passed over) group and the comparison group should start out alike.

Nothing was hidden in this open-label Exogenous HGH, sermorelin & older GHRPs (why they're passed over) study: the patients and staff both knew the treatment.

More than one site took part, so the patients came from several places.

The Exogenous HGH, sermorelin & older GHRPs (why they're passed over) group and the comparison group ran side by side rather than switching.

What Was Measured

The subject headings attached to it are Body Height, Growth, Growth Disorders, Growth Hormone, Infant, Low Birth Weight and Japan.

What This Means in Plain Language

The paper is a randomized, open-label and multicenter study of Exogenous HGH, sermorelin & older GHRPs (why they're passed over) in 34 patients.

With fewer than 40 people, it is a small study, so it is better read as an early signal for further research than as a settled answer.

The publication is from 2008 (Journal of pediatric endocrinology & metabolism : JPEM), a journal based in Germany.

More context: the Exogenous HGH, sermorelin & older GHRPs (why they're passed over) compound page, all human trials.

Our Notes on the Compound

Exogenous HGH, sermorelin & older GHRPs (why they're passed over): Constant levels suppress the body's own GHRH, raise somatostatin and dull pituitary response.

Related Pages

Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.