The role of parenteral glutamine supplement for surgical patient perioperatively: result of a single center, prospective and controlled study.

What Was Tested

Researchers studied Dipeptides in this randomized controlled trial publication.

The researchers conducted a prospective and case-controlled study to evaluate the impact of supplement of alanyl-glutamine dipeptide (Gln) in parenteral nutrition on perioperative immune and nutritional changes and clinical outcomes for patients undergoing gastrointestinal (GI) operations.

Who Took Part

The study group was 70 patients.

The age groups tagged for this paper are adults, middle-aged adults and older adults, both men and women.

During 2006, 70 patients undergoing GI surgeries were allocated equally into two groups.

One group received regular parenteral nutrition and the other received the same formulation and supplemented with the Gln; the two groups were isonitrogenous.

How the Study Was Run

The researchers set it up as a randomized study.

Because people in this Dipeptides study were split into groups at random, differences between the groups are less likely to reflect who happened to join each one.

Blood samples were collected on the morning of the day before the operation and on the morning 6 days after the operation and analyzed for immune and nutrition parameters.

What Was Measured

PubMed files the paper under topics including Case-Control Studies, Digestive System Diseases, Digestive System Neoplasms, Dipeptides, Hospital Mortality, Inflammation Mediators and Length of Stay.

What This Means in Plain Language

The paper is a randomized study of Dipeptides in 70 patients.

The abstract goes on to report its results in about 7 sentences; this page does not restate them, so read the paper for the findings and their limits.

The publication is from 2008 (Langenbeck's archives of surgery), a journal based in Germany.

More context: all human trials.