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An evaluation of the Italian version of the Fagerström Test for Nicotine Dependence.
Plain-language guide to PMID 18763437 (2008): double-blind randomized controlled trial of Therapeutic nicotine (patch, non-peptide) in 25 men.
Key Facts
- PMID
- 18763437
- Journal
- Psychological reports
- Year
- 2008
- Study type
- Randomized Controlled Trial
- Authors
- Ferketich AK et al. (3 authors)
- DOI
- 10.2466/pr0.102.3.687-694
What This Study Did, in Plain Language
What Was Tested
The paper reports a study of Therapeutic nicotine (patch, non-peptide), published as a randomized controlled trial.
This study examined the psychometric properties of an Italian version of the Fagerström Test for Nicotine Dependence in a sample of 593 smokers who were enrolled in a randomized Phase IV clinical trial to compare bupropion to placebo.
Why It Was Studied
This version was administered at baseline, and from each participant an expired air carbon monoxide (CO) measure was taken.
Spearman correlations between the Total score and CO concentration were.27 in the combined sample and.27 and.25 among men and women.
Who Took Part
The study group was 25 men.
By PubMed's age tags, the people studied were teenagers, both men and women.
How the Study Was Run
In design terms this was a randomized, double-blind and placebo-controlled study.
The men were allocated by chance, so the Therapeutic nicotine (patch, non-peptide) group and the comparison group should start out alike.
Neither the men nor the staff measuring them knew who was on Therapeutic nicotine (patch, non-peptide), so expectations could not easily colour the readings.
Some men received a placebo instead of Therapeutic nicotine (patch, non-peptide), giving a reference point.
What Was Measured
This version was administered at baseline, and from each participant an expired air carbon monoxide (CO) measure was taken.
Spearman correlations between the Total score and CO concentration were.27 in the combined sample and.27 and.25 among men and women.
Topics PubMed links to this paper include Italy, Surveys and Questionnaires and Tobacco Use Disorder.
What This Means in Plain Language
The paper is a randomized, double-blind and placebo-controlled study of Therapeutic nicotine (patch, non-peptide) in 25 men.
With fewer than 40 people, it is a small study, so it is better read as an early signal for further research than as a settled answer.
The publication is from 2008 (Psychological reports), a journal based in United States.
More context: the Therapeutic nicotine (patch, non-peptide) compound page, all human trials.
Our Notes on the Compound
Therapeutic nicotine (patch, non-peptide): Pure nicotine as a signaling tool, separated from smoking and vaping.
Related Pages
Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.