Evaluation of the American version of the 30-item Endometriosis Health Profile (EHP-30)

What Was Tested

Researchers studied Leuprolide in the context of endometriosis in this randomized controlled trial publication.

If the results of such trials in different countries are to be pooled, it is vitally important for researchers to know how comparable the instruments are across cultures.

In this study, the researchers evaluated the response rate, data quality, score reliability and scaling assumptions of the 30-item Endometriosis Health Profile (EHP-30) in the USA.

Who Took Part

The abstract describes 225 patients taking part.

The age groups tagged for this paper are adults, women only.

Data were obtained from a multi-centre study which recruited 225 patients from 43 clinic sites in the United States of America.

Questionnaires were self-completed by patients when they visited the clinics.

How the Study Was Run

The design is described as randomized.

Because people in this Leuprolide study were split into groups at random, differences between the groups are less likely to reflect who happened to join each one.

It was a randomised, evaluator-blinded, Phase III study.

In the evaluation of the EHP-30 reported here, the two groups (Depot Medroxyprogesterone Acetate [DMPA] and Leuprolide Acetate [LA]) are combined, and analyses are based on the data gained at baseline.

What Was Measured

Topics PubMed links to this paper include Antineoplastic Agents, Hormonal, Endometriosis, Health Status, Leuprolide, Medroxyprogesterone Acetate, Psychometrics and Quality of Life.

What This Means in Plain Language

The paper is a randomized study of Leuprolide in 225 patients in people with endometriosis.

Results are reported in around 6 sentences of the abstract; we leave them to the paper itself rather than summarise them.

The publication is from 2008 (Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation), a journal based in Netherlands.

More context: the Leuprolide compound page, Endometriosis research.