Comparison of inpatient insulin regimens with detemir plus aspart versus neutral protamine hagedorn plus regular in medical patients with type 2 diabetes

What Was Tested

Researchers studied Insulin Detemir and NPH Insulin (isophane) in this randomized controlled trial publication.

Studies comparing the use of basal bolus with insulin analogs vs. split-mixed regimens with human insulins in hospitalized patients with type 2 diabetes are lacking.

Who Took Part

The abstract describes 130 patients taking part.

By PubMed's age tags, the people studied were teenagers, young adults, adults, middle-aged adults, older adults and people over 80, both men and women.

Major study outcomes included differences in mean daily BG levels and frequency of hypoglycemic events between treatment groups.

How the Study Was Run

The design is described as randomized and multicenter.

The patients were allocated by chance, so the Insulin Detemir group and the comparison group should start out alike.

More than one site took part, so the patients came from several places.

What Was Measured

PubMed files the paper under topics including Diabetes Mellitus, Type 2, Hypoglycemic Agents, Inpatients, Insulin, Insulin Aspart, Insulin Detemir and Insulin, Isophane.

What This Means in Plain Language

The paper is a randomized and multicenter study of Insulin Detemir and NPH Insulin (isophane) in 130 patients.

Its findings take up roughly 4 sentences of the abstract and are left out here on purpose; the source paper is the place to read them.

The publication is from 2009 (The Journal of clinical endocrinology and metabolism), a journal based in United States.

More context: the Insulin Detemir compound page and the NPH Insulin (isophane) compound page, all human trials.