Population pharmacokinetic model for human growth hormone in adult patients in chronic dialysis compared with healthy subjects.

What Was Tested

The paper reports a study of Exogenous HGH, sermorelin & older GHRPs (why they're passed over), published as a clinical trial.

Who Took Part

The age groups tagged for this paper are adults, middle-aged adults and older adults, both men and women.

Various compartment models with first-order and Michaëlis-Menten absorption and elimination were explored.

Influence of the covariates subject group (ESRD/HV), gender, weight, and dialysis flow-rate on model parameters was examined.

How the Study Was Run

The design is described as parallel-group.

The Exogenous HGH, sermorelin & older GHRPs (why they're passed over) group and the comparison group ran side by side rather than switching.

What Was Measured

PubMed files the paper under topics including Absorption, Area Under Curve, Human Growth Hormone, Kidney Failure, Chronic, Recombinant Proteins and Renal Dialysis.

What This Means in Plain Language

The paper is a parallel-group study of Exogenous HGH, sermorelin & older GHRPs (why they're passed over).

Results are reported in around 6 sentences of the abstract; we leave them to the paper itself rather than summarise them.

The publication is from 2009 (Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society), a journal based in Scotland.

More context: the Exogenous HGH, sermorelin & older GHRPs (why they're passed over) compound page, all human trials.