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Effects of topical gluco-oligosaccharide and collagen tripeptide F in the treatment of sensitive atopic skin

Plain-language guide to PMID 19496838 (2009): double-blind randomized controlled trial study of Tripeptide-29 (Collagen Tripeptide), skin sensitivity and body aches on glp-1 medicines.

Key Facts

PMID
19496838
Journal
International journal of cosmetic science
Year
2009
Study type
Randomized Controlled Trial
Authors
Berardesca E et al. (4 authors)
DOI
10.1111/j.1468-2494.2009.00495.x

What This Study Did, in Plain Language

What Was Tested

This randomized controlled trial paper looks at Tripeptide-29 (Collagen Tripeptide) in the context of skin sensitivity and body aches on glp-1 medicines.

Forty female subjects (age, 30-59 years) affected by non-lesional atopic sensitive skin entered the study.

Skin sensitivity was determined by a dermatologist on the basis of medical history, stinging test, dermatological examination and a questionnaire.

Who Took Part

The age groups tagged for this paper are adults and middle-aged adults, women only.

How the Study Was Run

The design is described as randomized, double-blind and placebo-controlled.

The participants were allocated by chance, so the Tripeptide-29 (Collagen Tripeptide) group and the comparison group should start out alike.

As a double-blind Tripeptide-29 (Collagen Tripeptide) study, the assignments were hidden from both participants and investigators until the end.

The comparison arm used a placebo, so changes seen with Tripeptide-29 (Collagen Tripeptide) could be set against what happens without it.

The timeline in the abstract includes 4 weeks.

What Was Measured

Skin sensitivity was determined by a dermatologist on the basis of medical history, stinging test, dermatological examination and a questionnaire.

A treatment with the test products (active and placebo) was carried out for 4 weeks.

Topics PubMed links to this paper include Administration, Topical, Collagen Type I, Colony Count, Microbial, Dermatitis, Atopic, Oligosaccharides, Peptide Fragments and Staphylococcus aureus.

What This Means in Plain Language

The paper is a randomized, double-blind and placebo-controlled study of Tripeptide-29 (Collagen Tripeptide) in people with skin sensitivity and body aches on glp-1 medicines over 4 weeks.

The publication is from 2009 (International journal of cosmetic science), a journal based in England.

More context: the Tripeptide-29 (Collagen Tripeptide) compound page, Skin sensitivity and body aches on GLP-1 medicines research.

Our Notes on the Compound

Tripeptide-29 (Collagen Tripeptide): The collagen tripeptide Gly-Pro-Hyp, used in cosmetics and oral collagen supplements for skin hydration and elasticity.

Related Pages

Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.