Evaluation of effectiveness of local insulin injection in non-insulin-dependent diabetic patient with carpal tunnel syndrome

What Was Tested

This randomized controlled trial paper looks at NPH Insulin (isophane) in the context of carpal tunnel.

Carpal tunnel syndrome (CTS) has more incidences in diabetic patients.

Who Took Part

The study group was 50 patients.

By PubMed's age tags, the people studied were adults and middle-aged adults, both men and women.

The researchers carried out a prospective, randomized, single-blind, case-controlled study in these patients.

The researchers randomly selected 50 patients, 20 of whom had bilateral mild-moderate CTS.

How the Study Was Run

The design is described as randomized and single-blind.

The patients were allocated by chance, so the NPH Insulin (isophane) group and the comparison group should start out alike.

In this single-blind NPH Insulin (isophane) study one party knew the assignments and the other did not.

The timeline in the abstract includes 6 weeks.

Therefore the researchers had 70 hands and categorized them into two groups.

Electrodiagnostic study was performed for these two groups before treatment and 4 weeks after the last injection and physiotherapy.

The patients were followed up for 6 weeks.

What Was Measured

Topics PubMed links to this paper include Carpal Tunnel Syndrome, Diabetes Mellitus, Type 2, Hypoglycemic Agents, Injections, Intra-Articular, Insulin, Isophane, Median Nerve and Nerve Regeneration.

What This Means in Plain Language

The paper is a randomized and single-blind study of NPH Insulin (isophane) in 50 patients in people with carpal tunnel over 6 weeks.

Its findings take up roughly 5 sentences of the abstract and are left out here on purpose; the source paper is the place to read them.

The publication is from 2009 (Electromyography and clinical neurophysiology), a journal based in Belgium.

More context: the NPH Insulin (isophane) compound page, Carpal tunnel research.