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Effects of zinc supplementation on serum zinc and C-reactive protein concentrations in hemodialysis patients.

Plain-language guide to PMID 19541504 (2009): double-blind randomized controlled trial of Vitamin D, K2, Magnesium and Zinc in 32 men.

Key Facts

PMID
19541504
Journal
Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation
Year
2009
Study type
Randomized Controlled Trial
Authors
Rashidi AA et al. (4 authors)
DOI
10.1053/j.jrn.2009.04.005

What This Study Did, in Plain Language

What Was Tested

Researchers studied Vitamin D, K2, Magnesium and Zinc in this randomized controlled trial publication.

The researchers examined the effects of zinc supplementation on serum zinc and C-reactive protein concentrations in hemodialysis patients.

Who Took Part

According to the abstract, 32 men were involved.

PubMed indexes the participants as middle-aged adults, both men and women.

Patients were randomly divided into two groups.

How the Study Was Run

In design terms this was a randomized, double-blind and placebo-controlled study.

Random assignment meant chance, not the researchers, decided who got Vitamin D, K2, Magnesium and Zinc and who got the comparison, which limits bias.

As a double-blind Vitamin D, K2, Magnesium and Zinc study, the assignments were hidden from both participants and investigators until the end.

A placebo (an inactive look-alike) gave the Vitamin D, K2, Magnesium and Zinc group a baseline to be compared against.

This was a randomized, double-blinded, placebo-controlled clinical trial.

This study was conducted at the Shahid Faghihi and Namazi Dialysis Centers in Shiraz, Iran.

What Was Measured

Topics PubMed links to this paper include Astringents, C-Reactive Protein, Dietary Supplements, Kidney Failure, Chronic, Renal Dialysis, Zinc and Zinc Sulfate.

What This Means in Plain Language

The paper is a randomized, double-blind and placebo-controlled study of Vitamin D, K2, Magnesium and Zinc in 32 men.

With fewer than 40 people, it is a small study, so it is better read as an early signal for further research than as a settled answer.

The abstract goes on to report its results in about 6 sentences; this page does not restate them, so read the paper for the findings and their limits.

The publication is from 2009 (Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation), a journal based in United States.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.

Our Notes on the Compound

Vitamin D, K2, Magnesium and Zinc: Magnesium is described as required for AMPK to function.

Related Pages

Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.