Vitamin D and cognitive performance in adults: a systematic review.

What It Covers

The paper reports a study of Vitamin D, K2, Magnesium and Zinc, published as a systematic review.

The objective of this study was to systematically review all published data from the past 30 years which examined the association between serum 25OHD concentrations and cognitive performance in adults.

Why It Was Studied

Vitamin D receptors (VDR) are located in the human cortex and hippocampus, which are key areas for cognition.

An English and French Medline, PsycINFO and Cochrane Library search ranging from 1979 to 2008 indexed under the Medical Subject Heading (MeSH) terms 'Vitamin D' or 'Hydroxycholecalciferols' combined with the terms 'Dementia' or 'Cognition' or 'Cognition Disorders' or 'Delirium' or 'Memory' or 'Memory Disorders' or 'Orientation' or 'Executive Functions' or 'Attention' or 'Brain' or 'Neuropsychological Tests' was performed.

Who the Included Studies Covered

By PubMed's age tags, the people studied were adults.

Of the 99 selected studies, five observational studies met the selection criteria and were included in the final analysis.

What Was Measured

An English and French Medline, PsycINFO and Cochrane Library search ranging from 1979 to 2008 indexed under the Medical Subject Heading (MeSH) terms 'Vitamin D' or 'Hydroxycholecalciferols' combined with the terms 'Dementia' or 'Cognition' or 'Cognition Disorders' or 'Delirium' or 'Memory' or 'Memory Disorders' or 'Orientation' or 'Executive Functions' or 'Attention' or 'Brain' or 'Neuropsychological Tests' was performed.

The subject headings attached to it are Aging, Cognition, Receptors, Calcitriol and Vitamin D.

What This Means in Plain Language

This is a systematic review of Vitamin D, K2, Magnesium and Zinc.

The publication is from 2009 (European journal of neurology), a journal based in England.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.