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Magnesium supplementation during cardiopulmonary bypass to prevent junctional ectopic tachycardia after pediatric cardiac surgery: a randomized controlled study.

Plain-language guide to PMID 19819469 (2010): double-blind randomized controlled trial of Vitamin D, K2, Magnesium and Zinc in 99 children.

Key Facts

PMID
19819469
Journal
The Journal of thoracic and cardiovascular surgery
Year
2010
Study type
Randomized Controlled Trial
Authors
Manrique AM et al. (13 authors)
DOI
10.1016/j.jtcvs.2009.07.064

What This Study Did, in Plain Language

What Was Tested

This randomized controlled trial looks at Vitamin D, K2, Magnesium and Zinc.

The researchers analyzed the role of magnesium sulfate (MgSO(4)) supplementation during cardiopulmonary bypass in pediatric patients undergoing cardiac surgery, assessing the incidence of hypomagnesemia and the incidence of junctional ectopic tachycardia.

Who Took Part

The study group was 99 children.

PubMed indexes the participants as infants, young children, children and teenagers, both men and women.

The researchers performed a randomized, double-blind, controlled trial in 99 children.

How the Study Was Run

In design terms this was a randomized, double-blind and placebo-controlled study.

The children were allocated by chance, so the Vitamin D, K2, Magnesium and Zinc group and the comparison group should start out alike.

As a double-blind Vitamin D, K2, Magnesium and Zinc study, the assignments were hidden from both participants and investigators until the end.

Some children received a placebo instead of Vitamin D, K2, Magnesium and Zinc, giving a reference point.

What Was Measured

The subject headings attached to it are Anti-Arrhythmia Agents, Cardiopulmonary Bypass, Magnesium, Magnesium Sulfate, Postoperative Complications and Tachycardia, Ectopic Junctional.

What This Means in Plain Language

The paper is a randomized, double-blind and placebo-controlled study of Vitamin D, K2, Magnesium and Zinc in 99 children.

The abstract goes on to report its results in about 9 sentences; this page does not restate them, so read the paper for the findings and their limits.

The publication is from 2010 (The Journal of thoracic and cardiovascular surgery), a journal based in United States.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.

Our Notes on the Compound

Vitamin D, K2, Magnesium and Zinc: Magnesium is described as required for AMPK to function.

Related Pages

Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.