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Dynamics of body composition and bone in patients with juvenile idiopathic arthritis treated with growth hormone.

Plain-language guide to PMID 19880788 (2010): clinical trial of Exogenous HGH, sermorelin & older GHRPs (why they're passed over) in 12 patients.

Key Facts

PMID
19880788
Journal
The Journal of clinical endocrinology and metabolism
Year
2010
Study type
Clinical Trial
Authors
Bechtold S et al. (7 authors)
DOI
10.1210/jc.2009-0979

What This Study Did, in Plain Language

What Was Tested

This clinical trial looks at Exogenous HGH, sermorelin & older GHRPs (why they're passed over).

GH has a positive impact on growth, bone, and muscle development.

Who Took Part

The abstract describes 12 patients taking part.

The age groups tagged for this paper are children, teenagers, young adults and adults, both men and women.

In this longitudinal study, parameters of bone mineral density and geometry as well as muscle and fat cross-sectional area (CSA) in the nondominant forearm were recorded using peripheral quantitative computed tomography at yearly intervals until final height in 12 patients (seven females) receiving GH treatment.

Data at final height were compared with 13 patients (nine females) with JIA not treated with GH.

What Was Measured

The subject headings attached to it are Absorptiometry, Photon, Arthritis, Juvenile, Body Composition, Body Height, Bone Density, Bone and Bones and Growth Disorders.

What This Means in Plain Language

This is a clinical trial of Exogenous HGH, sermorelin & older GHRPs (why they're passed over) in 12 patients.

With fewer than 40 people, it is a small study, so it is better read as an early signal for further research than as a settled answer.

Its findings take up roughly 7 sentences of the abstract and are left out here on purpose; the source paper is the place to read them.

The publication is from 2010 (The Journal of clinical endocrinology and metabolism), a journal based in United States.

More context: the Exogenous HGH, sermorelin & older GHRPs (why they're passed over) compound page, all human trials.

Our Notes on the Compound

Exogenous HGH, sermorelin & older GHRPs (why they're passed over): Constant levels suppress the body's own GHRH, raise somatostatin and dull pituitary response.

Related Pages

Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.