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Effect of zinc supplementation on triglyceride, cholesterol, LDL, and HDL levels in zinc-deficient hemodialysis patients.
Plain-language guide to PMID 19925287 (2009): double-blind randomized controlled trial of Vitamin D, K2, Magnesium and Zinc.
Key Facts
- PMID
- 19925287
- Journal
- Renal failure
- Year
- 2009
- Study type
- Randomized Controlled Trial
- Authors
- Roozbeh J et al. (9 authors)
- DOI
- 10.3109/08860220903216055
What This Study Did, in Plain Language
What Was Tested
The paper reports a study of Vitamin D, K2, Magnesium and Zinc, published as a randomized controlled trial.
The purpose of this research was to study the effects of zinc supplementation on the concentration of serum zinc, total cholesterol, triglyceride, and cholesterol fractions (HDL, LDL) in HD patients.
Why It Was Studied
Zinc deficiency is known to occur in widely diverse areas of world.
It has now been recognized in many disease states, such as ESRD patients on maintenance hemodialysis (HD).
Who Took Part
PubMed indexes the participants as middle-aged adults.
In a double blind trial, the effects of oral zinc supplementation on the serum concentration of zinc, total cholesterol, HDL and LDL cholesterol, and triglyceride in HD patients were evaluated.
How the Study Was Run
The researchers set it up as a randomized and double-blind study.
Because people in this Vitamin D, K2, Magnesium and Zinc study were split into groups at random, differences between the groups are less likely to reflect who happened to join each one.
Neither the participants nor the staff measuring them knew who was on Vitamin D, K2, Magnesium and Zinc, so expectations could not easily colour the readings.
What Was Measured
PubMed files the paper under topics including Cholesterol, Cholesterol, HDL, Cholesterol, LDL, Deficiency Diseases, Dietary Supplements, Kidney Failure, Chronic and Renal Dialysis.
What This Means in Plain Language
The paper is a randomized and double-blind study of Vitamin D, K2, Magnesium and Zinc.
The abstract goes on to report its results in about 5 sentences; this page does not restate them, so read the paper for the findings and their limits.
The publication is from 2009 (Renal failure), a journal based in England.
More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.
Our Notes on the Compound
Vitamin D, K2, Magnesium and Zinc: Magnesium is described as required for AMPK to function.
Related Pages
Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.