← Human Trials & Peer-Reviewed Studies
Phytalgic, a food supplement, vs placebo in patients with osteoarthritis of the knee or hip: a randomised double-blind placebo-controlled clinical trial.
Plain-language guide to PMID 20015358 (2009): double-blind randomized controlled trial of Analgesics and Vitamin E in 81 patients.
Key Facts
- PMID
- 20015358
- Journal
- Arthritis research & therapy
- Year
- 2009
- Study type
- Randomized Controlled Trial
- Authors
- Jacquet A et al. (6 authors)
- DOI
- 10.1186/ar2891
- Registered trial
- NCT00666523
What This Study Did, in Plain Language
What Was Tested
This randomized controlled trial looks at Analgesics and Vitamin E.
The medicinal treatment of osteoarthritis (OA) is mostly symptomatic to relieve pain and incapacity with analgesics and non-steroidal anti-inflammatory drugs (NSAIDs), drugs with well-known risks.
This study tested the effects of a food supplement, Phytalgic, on pain and function in patients with osteoarthritis and their use of analgesic and NSAIDs.
Who Took Part
The study group was 81 patients.
PubMed indexes the participants as adults, middle-aged adults and older adults, both men and women.
How the Study Was Run
The researchers set it up as a randomized, double-blind, placebo-controlled and parallel-group study.
Random assignment meant chance, not the researchers, decided who got Analgesics and who got the comparison, which limits bias.
Neither the patients nor the staff measuring them knew who was on Analgesics, so expectations could not easily colour the readings.
Some patients received a placebo instead of Analgesics, giving a reference point.
The Analgesics group and the comparison group ran side by side rather than switching.
What Was Measured
This study tested the effects of a food supplement, Phytalgic, on pain and function in patients with osteoarthritis and their use of analgesic and NSAIDs.
The subject headings attached to it are Acetaminophen, Analgesics, Anti-Inflammatory Agents, Non-Steroidal, Dietary Supplements, Fish Oils, Osteoarthritis and Pain.
What This Means in Plain Language
The paper is a randomized, double-blind and placebo-controlled study of Analgesics and Vitamin E in 81 patients.
The abstract goes on to report its results in about 4 sentences; this page does not restate them, so read the paper for the findings and their limits.
The publication is from 2009 (Arthritis research & therapy), a journal based in England.
More context: all human trials.
Related Pages
Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.