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Growth hormone for in vitro fertilization.

Plain-language guide to PMID 20091500 (2010): meta-analysis of Exogenous HGH, sermorelin & older GHRPs (why they're passed over) and GHRH (Growth Hormone-Releasing Hormone).

Key Facts

PMID
20091500
Journal
The Cochrane database of systematic reviews
Year
2010
Study type
Meta-Analysis
Authors
Duffy JM et al. (5 authors)
DOI
10.1002/14651858.CD000099.pub3

What This Paper Covers, in Plain Language

What It Covers

This meta-analysis looks at Exogenous HGH, sermorelin & older GHRPs (why they're passed over) and GHRH (Growth Hormone-Releasing Hormone).

The researchers searched the Cochrane Menstrual Disorders and Subfertility Groups trials register (June 2009), the Cochrane Central Register of Controlled Trials (Cochrane Library Issue 2, 2009), MEDLINE (1966 to June 2009), EMBASE (1988 to June 2009) and Biological Abstracts (1969 to June 2009).

Assessment of trial risk of bias and extraction of relevant data was performed independently by two reviewers.

Who the Included Studies Covered

PubMed tags the participants as women only.

All randomised controlled trials were included if they addressed the research question and provided outcome data for intervention and control participants.

What Was Measured

Assessment of trial risk of bias and extraction of relevant data was performed independently by two reviewers.

The subject headings attached to it are Chemotherapy, Adjuvant, Fertilization in Vitro, Growth Hormone-Releasing Hormone, Human Growth Hormone, Infertility, Female, Live Birth and Ovulation Induction.

What This Means in Plain Language

This is a meta-analysis of Exogenous HGH, sermorelin & older GHRPs (why they're passed over) and GHRH (Growth Hormone-Releasing Hormone).

Its findings take up roughly 6 sentences of the abstract and are left out here on purpose; the source paper is the place to read them.

The publication is from 2010 (The Cochrane database of systematic reviews), a journal based in England.

More context: the Exogenous HGH, sermorelin & older GHRPs (why they're passed over) compound page and the GHRH (Growth Hormone-Releasing Hormone) compound page, all human trials.

Our Notes on the Compounds

Exogenous HGH, sermorelin & older GHRPs (why they're passed over): Constant levels suppress the body's own GHRH, raise somatostatin and dull pituitary response.

GHRH (Growth Hormone-Releasing Hormone): The 44-amino-acid hypothalamic hormone that tells the pituitary to release growth hormone; sermorelin and tesamorelin are analogs.

Related Pages

Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.