Measurement of zinc absorption from meals: comparison of extrinsic zinc labeling and independent measurements of dietary zinc absorption.

What Was Tested

This clinical trial looks at Zinc.

To compare determination of the quantity of zinc absorbed (TAZ(extrinsic)) using measurements of FAZ(extrinsic) with results of simultaneous determinations of dietary zinc absorbed (TAZ(metabolic)) that are not dependent on labeling ingested food with an extrinsic tracer (modified metabolic balance technique).

Why It Was Studied

Extrinsic labeling techniques are typically used to measure fractional absorption of zinc (FAZ(extrinsic)) but none have been adequately evaluated.

Who Took Part

By PubMed's age tags, the people studied were young adults, adults and middle-aged adults, women only.

(70)Zn was administered orally with all meals for 6 consecutive days to 21 healthy, free-living adult women consuming a constant diet.

How the Study Was Run

(68)Zn and (67)Zn were administered intravenously.

FAZ(extrinsic) was measured using a dual isotope tracer ratio technique and multiplied by dietary zinc to give TAZ(extrinsic).

TAZ(metabolic) was determined by addition of net absorption of zinc and endogenous fecal zinc, the latter determined by an isotope dilution technique.

What Was Measured

Extrinsic labeling techniques are typically used to measure fractional absorption of zinc (FAZ(extrinsic)) but none have been adequately evaluated.

The subject headings attached to it are Diet Records, Food, Intestinal Absorption, Reproducibility of Results, Staining and Labeling, Zinc and Zinc Isotopes.

What This Means in Plain Language

This is a clinical trial of Zinc.

Results are reported in around 4 sentences of the abstract; we leave them to the paper itself rather than summarise them.

The publication is from 2009 (International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition), a journal based in Singapore.

More context: the related Vitamin D, K2, Magnesium and Zinc library page, all human trials.