The effect of human chorionic gonadotropin and pregnancy on the circulating level of relaxin

What Was Tested

The paper reports a study of hCG (human chorionic gonadotropin) and Relaxin (Serelaxin), published as a randomized controlled trial.

The effect of hCG and pregnancy on the circulating levels of relaxin was investigated in 48 women undergoing in vitro fertilization and embryo transfer (ET) for the treatment of infertility.

Samples of peripheral blood were taken on days -4, 6, and 10.

Who Took Part

According to the abstract, 48 women were involved.

PubMed tags the participants as women only.

The subjects were allocated retrospectively to 1 of 4 groups: no pregnancy, no hCG (NP); pregnancy, no hCG (P); no pregnancy, hCG (NPH); and pregnancy, hCG (PH).

How the Study Was Run

The researchers set it up as a randomized and placebo-controlled study.

The women were allocated by chance, so the hCG (human chorionic gonadotropin) group and the comparison group should start out alike.

A placebo (an inactive look-alike) gave the hCG (human chorionic gonadotropin) group a baseline to be compared against.

What Was Measured

The effect of hCG and pregnancy on the circulating levels of relaxin was investigated in 48 women undergoing in vitro fertilization and embryo transfer (ET) for the treatment of infertility.

PubMed files the paper under topics including Chorionic Gonadotropin, Embryo Transfer, Embryonic Development, Estradiol, Fertilization in Vitro, Infertility, Female and Progesterone.

What This Means in Plain Language

The paper is a randomized and placebo-controlled study of hCG (human chorionic gonadotropin) and Relaxin (Serelaxin) in 48 women.

The publication is from 1991 (The Journal of clinical endocrinology and metabolism), a journal based in United States.

More context: the hCG (human chorionic gonadotropin) compound page and the Relaxin (Serelaxin) compound page, all human trials.