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A randomised study on the clinical progress of high-risk elective major gastrointestinal surgery patients treated with olive oil-based parenteral nutrition with or without a fish oil supplement.
Plain-language guide to PMID 20350344 (2010): double-blind randomized controlled trial of Anti-Infective Agents.
Key Facts
- PMID
- 20350344
- Journal
- The British journal of nutrition
- Year
- 2010
- Study type
- Randomized Controlled Trial
- Authors
- Badía-Tahull MB et al. (7 authors)
- DOI
- 10.1017/S0007114510001066
What This Study Did, in Plain Language
What Was Tested
Researchers studied Anti-Infective Agents in this randomized controlled trial publication.
The primary aim of the present study was the assessment of infection in patients who underwent major high-risk elective gastrointestinal surgery receiving postoperatively fish oil (FO)-supplemented parenteral nutrition (PN), compared with those receiving a standard olive oil (OO) emulsion.
Why It Was Studied
The secondary aims were the assessment of anti-inflammatory response and evaluation of tolerance and safety of these emulsions.
A prospective, randomised, double-blind study was performed in patients requiring at least 5 d of PN.
Who Took Part
PubMed indexes the participants as adults, middle-aged adults, older adults and people over 80, both men and women.
How the Study Was Run
The design is described as randomized and double-blind.
Because people in this Anti-Infective Agents study were split into groups at random, differences between the groups are less likely to reflect who happened to join each one.
Blinding on both sides kept the participants and researchers unaware of who received Anti-Infective Agents.
What Was Measured
The secondary aims were the assessment of anti-inflammatory response and evaluation of tolerance and safety of these emulsions.
End points were outcome measures (mortality, sepsis, infection, hospitalisation days and PN duration), inflammatory response (C-reactive protein (CRP), prealbumin and leucocytes) and safety (TAG and glucose metabolism, and liver and kidney function).
PubMed files the paper under topics including Anti-Infective Agents, Elective Surgical Procedures, Emulsions, Fat Emulsions, Intravenous, Fish Oils, Gastrointestinal Tract and Incidence.
What This Means in Plain Language
The paper is a randomized and double-blind study of Anti-Infective Agents.
The publication is from 2010 (The British journal of nutrition), a journal based in England.
More context: all human trials.
Related Pages
Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.