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The effects of growth hormone on body composition and physical performance in recreational athletes: a randomized trial.
Plain-language guide to PMID 20439575 (2010): randomized controlled trial of Exogenous HGH, sermorelin & older GHRPs (why they're passed over) in 63 men.
Key Facts
- PMID
- 20439575
- Journal
- Annals of internal medicine
- Year
- 2010
- Study type
- Randomized Controlled Trial
- Authors
- Meinhardt U et al. (8 authors)
- DOI
- 10.7326/0003-4819-152-9-201005040-00007
What This Study Did, in Plain Language
What Was Tested
Researchers studied Exogenous HGH, sermorelin & older GHRPs (why they're passed over) in this randomized controlled trial publication.
To determine the effect of growth hormone alone or with testosterone on body composition and measures of performance.
Why It Was Studied
Growth hormone is widely abused by athletes, frequently with androgenic steroids.
Its effects on performance are unclear.
Who Took Part
According to the abstract, 63 men were involved.
PubMed indexes the participants as teenagers, young adults and adults, both men and women.
96 recreationally trained athletes (63 men and 33 women) with a mean age of 27.9 years (SD, 5.7).
How the Study Was Run
The design is described as randomized and placebo-controlled.
Random assignment meant chance, not the researchers, decided who got Exogenous HGH, sermorelin & older GHRPs (why they're passed over) and who got the comparison, which limits bias.
Some men received a placebo instead of Exogenous HGH, sermorelin & older GHRPs (why they're passed over), giving a reference point.
Randomization was computer-generated with concealed allocation.
Clinical research facility in Sydney, Australia.
Body composition variables (fat mass, lean body mass, extracellular water mass, and body cell mass) and physical performance variables (endurance [maximum oxygen consumption], strength [dead lift], power [jump height], and sprint capacity [Wingate value]).
What Was Measured
The subject headings attached to it are Adipose Tissue, Androgens, Athletic Performance, Body Composition, Body Mass Index, Body Water and Extracellular Fluid.
What This Means in Plain Language
The paper is a randomized and placebo-controlled study of Exogenous HGH, sermorelin & older GHRPs (why they're passed over) in 63 men.
Results are reported in around 5 sentences of the abstract; we leave them to the paper itself rather than summarise them.
The publication is from 2010 (Annals of internal medicine), a journal based in United States.
More context: the Exogenous HGH, sermorelin & older GHRPs (why they're passed over) compound page, all human trials.
Our Notes on the Compound
Exogenous HGH, sermorelin & older GHRPs (why they're passed over): Constant levels suppress the body's own GHRH, raise somatostatin and dull pituitary response.
Related Pages
Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.