← Human Trials & Peer-Reviewed Studies
Maternal gestational zinc supplementation does not influence multiple aspects of child development at 54 mo of age in Peru.
Plain-language guide to PMID 20484451 (2010): double-blind randomized controlled trial of Vitamin D, K2, Magnesium and Zinc in 205 children.
Key Facts
- PMID
- 20484451
- Journal
- The American journal of clinical nutrition
- Year
- 2010
- Study type
- Randomized Controlled Trial
- Authors
- Caulfield LE et al. (8 authors)
- DOI
- 10.3945/ajcn.2010.29407
What This Study Did, in Plain Language
What Was Tested
The paper reports a study of Vitamin D, K2, Magnesium and Zinc, published as a randomized controlled trial.
The objective was to evaluate differences in cognitive, social, and behavioral function in Peruvian children at 54 mo of age whose mothers participated during pregnancy in a zinc supplementation trial.
Who Took Part
The abstract describes 205 children taking part.
PubMed indexes the participants as young children, women only.
Following a standardized protocol, the researchers assessed children's intelligence, language and number skills, representational ability, interpersonal understanding, and adaptive behavior and behavioral adjustment.
The researchers also assessed aspects of the mother (eg, age, education, verbal intelligence, stresses, and social support in parenting) and the home environment [HOME (Home Observation for the Measurement of the Environment) inventory].
How the Study Was Run
The researchers set it up as a randomized and double-blind study.
The children were allocated by chance, so the Vitamin D, K2, Magnesium and Zinc group and the comparison group should start out alike.
Neither the children nor the staff measuring them knew who was on Vitamin D, K2, Magnesium and Zinc, so expectations could not easily colour the readings.
What Was Measured
PubMed files the paper under topics including Child Development, Dietary Supplements, Educational Status, Ferrous Compounds, Folic Acid, Intelligence and Interpersonal Relations.
What This Means in Plain Language
The paper is a randomized and double-blind study of Vitamin D, K2, Magnesium and Zinc in 205 children.
The abstract goes on to report its results in about 3 sentences; this page does not restate them, so read the paper for the findings and their limits.
The publication is from 2010 (The American journal of clinical nutrition), a journal based in United States.
More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.
Our Notes on the Compound
Vitamin D, K2, Magnesium and Zinc: Magnesium is described as required for AMPK to function.
Related Pages
Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.