Increased neck soft tissue mass and worsening of obstructive sleep apnea after growth hormone treatment in men with abdominal obesity.

What Was Tested

Researchers studied Exogenous HGH, sermorelin & older GHRPs (why they're passed over) in the context of sleep apnea (obstructive) in this randomized controlled trial publication.

To study the effect of GH treatment on OSA in abdominally obese men with impaired glucose tolerance.

Why It Was Studied

Risk factors for obstructive sleep apnea (OSA) are male gender, obesity and abnormalities in neck soft tissue mass.

Adults with abdominal obesity have markedly suppressed GH secretion.

Who Took Part

The age groups tagged for this paper are adults, middle-aged adults and older adults, men only.

Forty men with abdominal obesity and glucose intolerance were randomized in a prospective, 12-month double-blind trial to receive either GH or placebo.

The treatment groups had similar BMI and waist circumference.

How the Study Was Run

The design is described as randomized, double-blind and placebo-controlled.

Random assignment meant chance, not the researchers, decided who got Exogenous HGH, sermorelin & older GHRPs (why they're passed over) and who got the comparison, which limits bias.

Blinding on both sides kept the participants and researchers unaware of who received Exogenous HGH, sermorelin & older GHRPs (why they're passed over).

The comparison arm used a placebo, so changes seen with Exogenous HGH, sermorelin & older GHRPs (why they're passed over) could be set against what happens without it.

What Was Measured

PubMed files the paper under topics including Body Composition, Body Weights and Measures, Glucose Intolerance, Human Growth Hormone, Insulin-Like Growth Factor I, Neck and Obesity, Abdominal.

What This Means in Plain Language

The paper is a randomized, double-blind and placebo-controlled study of Exogenous HGH, sermorelin & older GHRPs (why they're passed over) in people with sleep apnea (obstructive).

Its findings take up roughly 7 sentences of the abstract and are left out here on purpose; the source paper is the place to read them.

The publication is from 2010 (Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine), a journal based in United States.

More context: the Exogenous HGH, sermorelin & older GHRPs (why they're passed over) compound page, Sleep apnea (obstructive) research.