A randomized, controlled trial of vitamin D supplementation upon musculoskeletal health in postmenarchal females.

What Was Tested

Researchers studied Vitamin D, K2, Magnesium and Zinc in this randomized controlled trial publication.

The aim was to determine the effect of vitamin D supplementation on the adolescent musculoskeletal system.

Why It Was Studied

There has been a resurgence of vitamin D deficiency rickets throughout the developed world, with infants and adolescents being primarily affected.

Adolescence is a crucial period for muscle and bone mineral accumulation.

Who Took Part

By PubMed's age tags, the people studied were children and teenagers, women only.

Postmenarchal 12- to 14-yr-old females participated in the trial.

How the Study Was Run

The researchers set it up as a randomized and double-blind study.

Random assignment meant chance, not the researchers, decided who got Vitamin D, K2, Magnesium and Zinc and who got the comparison, which limits bias.

Blinding on both sides kept the participants and researchers unaware of who received Vitamin D, K2, Magnesium and Zinc.

The researchers conducted a community-based, double-blind, randomized controlled trial in a secondary school.

Ninety-nine were screened, 73 were included in randomized controlled trial, and 69 completed the trial.

There were no adverse events.

What Was Measured

Topics PubMed links to this paper include Absorptiometry, Photon, Bone Density, Dietary Supplements, Feasibility Studies, Hand Strength, Health Status and Menarche.

What This Means in Plain Language

The paper is a randomized and double-blind study of Vitamin D, K2, Magnesium and Zinc.

The abstract goes on to report its results in about 7 sentences; this page does not restate them, so read the paper for the findings and their limits.

The publication is from 2010 (The Journal of clinical endocrinology and metabolism), a journal based in United States.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.