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Vitamin D status and PTH in young men: a cross-sectional study on associations with bone mineral density, body composition and glucose metabolism.

Plain-language guide to PMID 20718769 (2010): clinical trial of Vitamin D, K2, Magnesium and Zinc in 783 men.

Key Facts

PMID
20718769
Journal
Clinical endocrinology
Year
2010
Study type
Clinical Trial
Authors
Frost M et al. (6 authors)
DOI
10.1111/j.1365-2265.2010.03847.x
Registered trial
NCT00150163

What This Study Did, in Plain Language

What Was Tested

The paper reports a study of Vitamin D, K2, Magnesium and Zinc, published as a clinical trial.

Although vitamin D and bone metabolism are closely related, few studies have addressed the effects of vitamin D status on bone in men at time of peak bone mass.

The objectives of this study were to evaluate the prevalence of vitamin D inadequacy in a cross-sectional study in young men and the effects of vitamin D and parathyroid hormone (PTH) on bone mass, bone markers and metabolic function.

Bone mineral density (BMD) of the total hip, femoral neck and lumbar spine was measured. dual-energy X-ray absorptiometry was used to evaluate total body fat mass (BFAT).

Who Took Part

The study group was 783 men.

By PubMed's age tags, the people studied were adults, men only.

The study population consisted of 783 men aged 20-29 years.

How the Study Was Run

Visceral fat mass and abdominal subcutaneous fat mass (ViFM and ScFM) were assessed using magnetic resonance imaging.

A radioimmunoassay was used to measure the level of 25-hydroxy vitamin D (25OHD).

What Was Measured

Topics PubMed links to this paper include Absorptiometry, Photon, Adipose Tissue, Body Composition, Bone Density, Calcium, Cross-Sectional Studies and Denmark.

What This Means in Plain Language

This is a clinical trial of Vitamin D, K2, Magnesium and Zinc in 783 men.

With several hundred people or more, it is a fairly large study for this kind of research.

The abstract goes on to report its results in about 6 sentences; this page does not restate them, so read the paper for the findings and their limits.

The publication is from 2010 (Clinical endocrinology), a journal based in England.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.

Our Notes on the Compound

Vitamin D, K2, Magnesium and Zinc: Magnesium is described as required for AMPK to function.

Related Pages

Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.