Effect of an antioxidant-rich multivitamin supplement in cystic fibrosis.

What Was Tested

This clinical trial looks at Antioxidants and Vitamins.

Despite supplementation with standard multivitamins and pancreatic enzymes, deficiencies of vitamins D and K and antioxidants are common in cystic fibrosis (CF).

Who Took Part

The study group was 14 subjects.

By PubMed's age tags, the people studied were children, teenagers and young adults, both men and women.

Both pancreatic sufficient and insufficient subjects were enrolled.

How the Study Was Run

The design is described as open-label.

Being open-label, the Antioxidants study did not mask who received what.

Plasma vitamin and antioxidant levels, urine 8-isoprostane levels, anthropometric measures, and pulmonary function were determined at baseline, 6 and 12 weeks.

What Was Measured

PubMed files the paper under topics including Antioxidants, Body Mass Index, Cystic Fibrosis, Dietary Supplements, Dinoprost, Exocrine Pancreatic Insufficiency and Oxidative Stress.

What This Means in Plain Language

The paper is an open-label study of Antioxidants and Vitamins in 14 subjects.

With fewer than 40 people, it is a small study, so it is better read as an early signal for further research than as a settled answer.

The abstract goes on to report its results in about 7 sentences; this page does not restate them, so read the paper for the findings and their limits.

The publication is from 2011 (Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society), a journal based in Netherlands.

More context: all human trials.