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A randomized controlled trial of the effects of vitamin D on muscle strength and mobility in older women with vitamin D insufficiency.

Plain-language guide to PMID 21054285 (2010): double-blind randomized controlled trial of Vitamin D, K2, Magnesium and Zinc.

Key Facts

PMID
21054285
Journal
Journal of the American Geriatrics Society
Year
2010
Study type
Randomized Controlled Trial
Authors
Zhu K et al. (5 authors)
DOI
10.1111/j.1532-5415.2010.03142.x

What This Study Did, in Plain Language

What Was Tested

Researchers studied Vitamin D, K2, Magnesium and Zinc in this randomized controlled trial publication.

To evaluate the effects of vitamin D treatment on muscle strength and mobility in older women with vitamin D insufficiency.

Who Took Part

By PubMed's age tags, the people studied were older adults and people over 80, women only.

Three hundred two community-dwelling ambulant elderly women aged 70 to 90 with a serum 25-hydroxyvitamin D (25(OH)D) concentration less than 24 ng/mL.

How the Study Was Run

The researchers set it up as a randomized, double-blind and placebo-controlled study.

Because people in this Vitamin D, K2, Magnesium and Zinc study were split into groups at random, differences between the groups are less likely to reflect who happened to join each one.

Blinding on both sides kept the participants and researchers unaware of who received Vitamin D, K2, Magnesium and Zinc.

Some participants received a placebo instead of Vitamin D, K2, Magnesium and Zinc, giving a reference point.

One-year population-based, double-blind, randomized, controlled trial.

Lower limb muscle strength and mobility as assessed using the Timed Up and Go Test (TUAG).

What Was Measured

Topics PubMed links to this paper include Mobility Limitation, Muscle Strength, Vitamin D, Vitamin D Deficiency and Vitamins.

What This Means in Plain Language

The paper is a randomized, double-blind and placebo-controlled study of Vitamin D, K2, Magnesium and Zinc.

Its findings take up roughly 6 sentences of the abstract and are left out here on purpose; the source paper is the place to read them.

The publication is from 2010 (Journal of the American Geriatrics Society), a journal based in United States.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.

Our Notes on the Compound

Vitamin D, K2, Magnesium and Zinc: Magnesium is described as required for AMPK to function.

Related Pages

Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.