[The effect of the external chest compression appliance (AutoPulse) on cardiac arrest in the emergency department and influence on blood gas and N-terminal B-type natriuretic peptide]

What Was Tested

The paper reports a study of BNP (Nesiritide), published as a controlled clinical trial.

To investigate the value of AutoPulse in the patients with cardiac arrest (CA) in emergency department.

Who Took Part

By PubMed's age tags, the people studied were adults, middle-aged adults and older adults, both men and women.

Patients with CA seen in the Emergency Department of Chaoyang Hospital, Affiliated to Capital Medical University from September 2008 to August 2009 were divided into standard manual external chest compression group (n=42) and mechanical chest compression group with AutoPulse (n=43), based on the method of the external chest compression.

Tracheal intubation was performed and mechanical ventilation instituted in all the patients.

How the Study Was Run

Other rescue measures, such as intravenous infusion of fluids, electrocardiogram, electric shock for defibrillation were performed following the cardiopulmonary guideline of 2005.

The patients with restoration of spontaneous circulation in 20 minutes were excluded.

Among patients with resuscitation over 20 minutes, there were 29 cases in AutoPulse group and 28 cases in standard manual external chest compression group.

The blood gas and N-terminal B-type natriuretic peptide (NT-proBNP) from the blood samples obtained from the femoral artery 20 minutes after resuscitation were determined, and the survival rate at 2 hours and 24 hours in both groups was recorded.

What Was Measured

Topics PubMed links to this paper include Blood Gas Analysis, Cardiopulmonary Resuscitation, Emergencies, Heart Arrest and Natriuretic Peptide, Brain.

What This Means in Plain Language

This is a controlled clinical trial of BNP (Nesiritide).

The abstract goes on to report its results in about 5 sentences; this page does not restate them, so read the paper for the findings and their limits.

The publication is from 2010 (Zhongguo wei zhong bing ji jiu yi xue = Chinese critical care medicine = Zhongguo weizhongbing jijiuyixue), a journal based in China.

More context: the BNP (Nesiritide) compound page, all human trials.