Magnesium supplementation improves indicators of low magnesium status and inflammatory stress in adults older than 51 years with poor quality sleep.

What Was Tested

This randomized controlled trial looks at Vitamin D, K2, Magnesium and Zinc.

Some animal findings indicate that a moderate magnesium deficiency, similar to which apparently commonly occurs in humans, may enhance inflammatory or oxidative stress induced by other factors, including disrupted sleep/sleep deprivation.

Thus, an experiment was performed with 100 adults (22 males and 78 females) aged 59 ± 8 years (range 51 to 85 years) with poor sleep quality revealed by a Pittsburg Sleep Quality Index (PSQI) score higher than five.

Who Took Part

The abstract describes 100 adults taking part.

PubMed indexes the participants as middle-aged adults, older adults and people over 80, both men and women.

How the Study Was Run

The researchers set it up as a randomized and placebo-controlled study.

Random assignment meant chance, not the researchers, decided who got Vitamin D, K2, Magnesium and Zinc and who got the comparison, which limits bias.

Some adults received a placebo instead of Vitamin D, K2, Magnesium and Zinc, giving a reference point.

What Was Measured

Thus, an experiment was performed with 100 adults (22 males and 78 females) aged 59 ± 8 years (range 51 to 85 years) with poor sleep quality revealed by a Pittsburg Sleep Quality Index (PSQI) score higher than five.

The participants were randomly assigned to two groups matched by gender, age, and overall PSQI score.

Topics PubMed links to this paper include Dietary Supplements, Inflammation, Magnesium, Magnesium Deficiency, Sleep Wake Disorders and Stress, Physiological.

What This Means in Plain Language

The paper is a randomized and placebo-controlled study of Vitamin D, K2, Magnesium and Zinc in 100 adults.

The publication is from 2010 (Magnesium research), a journal based in England.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.