Amylin and selective glucoregulatory peptide alterations during prolonged exercise

What Was Tested

The paper reports a study of Amylin (Islet Amyloid Polypeptide), published as a clinical trial.

This study aimed to determine the effects of 90 min of treadmill exercise on amylin and other glucoregulatory hormone responses in a postprandial state.

Why It Was Studied

Amylin is a pancreatic β-cell peptide that facilitates the regulation of blood glucose concentration by inhibiting release of glucagon and modulating gastric emptying.

Prolonged exercise may alter amylin and aid in the maintenance of blood glucose concentration; however, no studies have investigated the effects of prolonged exercise on amylin.

Who Took Part

PubMed indexes the participants as young adults and adults, men only.

Eight young healthy males completed a preliminary trial for VO2max and body composition determination and subsequent experimental and control trials in a counterbalanced manner.

The experimental trial subjects arrived at the laboratory at 8:00 a.m., 1 h after consumption of a standard nutrient beverage (Ensure Plus®).

How the Study Was Run

Blood samples were collected twice before exercise, every 18 min during exercise, and every 20 min during 1 h of recovery.

A resting control trial was conducted in an identical manner without VO2 assessment.

What Was Measured

PubMed files the paper under topics including Blood Glucose, C-Peptide, Exercise, Glucagon, Hydrocortisone, Insulin and Islet Amyloid Polypeptide.

What This Means in Plain Language

This is a clinical trial of Amylin (Islet Amyloid Polypeptide).

The abstract goes on to report its results in about 5 sentences; this page does not restate them, so read the paper for the findings and their limits.

The publication is from 2011 (Medicine and science in sports and exercise), a journal based in United States.

More context: the Amylin (Islet Amyloid Polypeptide) compound page, all human trials.