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Diet induced thermogenesis, fat oxidation and food intake following sequential meals: influence of calcium and vitamin D.
Plain-language guide to PMID 21276644 (2011): crossover randomized controlled trial of Vitamin D, K2, Magnesium and Zinc.
Key Facts
- PMID
- 21276644
- Journal
- Clinical nutrition (Edinburgh, Scotland)
- Year
- 2011
- Study type
- Randomized Controlled Trial
- Authors
- Ping-Delfos WC et al. (2 authors)
- DOI
- 10.1016/j.clnu.2010.11.006
What This Study Did, in Plain Language
What Was Tested
Researchers studied Vitamin D, K2, Magnesium and Zinc in this randomized controlled trial publication.
The mechanisms linking dietary calcium and vitamin D to body weight regulation require confirmation.
Who Took Part
PubMed indexes the participants as middle-aged adults, both men and women.
Eleven subjects, aged (mean ± SEM) 54 ± 1.2 y and BMI 31 ± 2.4 kg/m(2), participated in a randomised within-subject, sequential meal protocol comparing a low calcium trial (LCT) to an isoenergetic high calcium trial (HCT).
Diet induced thermogenesis (DIT), fat oxidation rates (FOR), serum leptin, subjective feelings of hunger/satiety were measured at fasting and hourly over 8 h.
How the Study Was Run
The design is described as randomized and crossover.
The participants were allocated by chance, so the Vitamin D, K2, Magnesium and Zinc group and the comparison group should start out alike.
In the crossover set-up each of the participants took both Vitamin D, K2, Magnesium and Zinc and the comparison in turn, acting as their own control.
Spontaneous food intake at a buffet and over the following 30 h was recorded.
Postprandial responses, calculated as change (Δ) from baseline for each meal, were analysed by paired t-tests and 2 × 2 repeated measures ANOVA.
What Was Measured
PubMed files the paper under topics including Appetite Regulation, Calcium, Dietary, Dairy Products, Dietary Carbohydrates, Dietary Fats, Eating and Leptin.
What This Means in Plain Language
The paper is a randomized and crossover study of Vitamin D, K2, Magnesium and Zinc.
Results are reported in around 4 sentences of the abstract; we leave them to the paper itself rather than summarise them.
The publication is from 2011 (Clinical nutrition (Edinburgh, Scotland)), a journal based in England.
More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.
Our Notes on the Compound
Vitamin D, K2, Magnesium and Zinc: Magnesium is described as required for AMPK to function.
Related Pages
Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.