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Increase in serum growth hormone induced by electrical stimulation of muscle combined with blood flow restriction.

Plain-language guide to PMID 21399959 (2011): randomized controlled trial of Exogenous HGH, sermorelin & older GHRPs (why they're passed over).

Key Facts

PMID
21399959
Journal
European journal of applied physiology
Year
2011
Study type
Randomized Controlled Trial
Authors
Inagaki Y et al. (4 authors)
DOI
10.1007/s00421-011-1899-y

What This Study Did, in Plain Language

What Was Tested

Researchers studied Exogenous HGH, sermorelin & older GHRPs (why they're passed over) in this randomized controlled trial publication.

The purpose of this study was to investigate the role of muscle metaboreflex on exercise-induced growth hormone (GH) secretion.

Just before the exercise, proximal portion of either a stimulated thigh (ST) or a non-stimulated thigh (NT) was compressed at 150 mmHg with an air-pressure cuff for the purpose of BFR.

Why It Was Studied

In order to accumulate metabolites within exercised muscle with minimized central motor activity, electromyostimulation (EMS) was performed combined with blood flow restriction (BFR).

Seven men performed one-legged isometric knee extension evoked by EMS (frequency, 20 Hz; pulse duration, 400 μs; on-off ratio, 3-1 s).

Who Took Part

By PubMed's age tags, the people studied were young adults and adults, men only.

How the Study Was Run

The design is described as randomized.

Random assignment meant chance, not the researchers, decided who got Exogenous HGH, sermorelin & older GHRPs (why they're passed over) and who got the comparison, which limits bias.

What Was Measured

Topics PubMed links to this paper include Constriction, Electric Stimulation, Electromyography, Human Growth Hormone, Lactic Acid, Leg and Muscle Contraction.

What This Means in Plain Language

The paper is a randomized study of Exogenous HGH, sermorelin & older GHRPs (why they're passed over).

The publication is from 2011 (European journal of applied physiology), a journal based in Germany.

More context: the Exogenous HGH, sermorelin & older GHRPs (why they're passed over) compound page, all human trials.

Our Notes on the Compound

Exogenous HGH, sermorelin & older GHRPs (why they're passed over): Constant levels suppress the body's own GHRH, raise somatostatin and dull pituitary response.

Related Pages

Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.