Decreased nocturnal growth hormone secretion and sleep fragmentation in combat-related posttraumatic stress disorder; potential predictors of impaired memory consolidation.

What Was Tested

This clinical trial looks at Exogenous HGH, sermorelin & older GHRPs (why they're passed over).

Healthy sleep facilitates the consolidation of newly acquired memories.

Although patients with posttraumatic stress disorder (PTSD) often complain of sleep disturbances and memory deficits, the interrelatedness of these symptoms is not well understood.

Who Took Part

PubMed indexes the participants as adults and middle-aged adults, men only.

While sleep EEG was being monitored, 13 veterans with PTSD, 15 trauma controls (TC) and 15 healthy controls (HC) slept with an iv catheter, through which blood was collected every 20 min from 23:00 h to 08:00 h.

How the Study Was Run

Declarative memory encoding was assessed with the 15 word task before sleep, and consolidation was assessed the next morning by a free recall.

What Was Measured

The researchers conducted a controlled study in which the researchers assessed sleep fragmentation, nocturnal secretion of GH, and memory consolidation in patients with PTSD.

Topics PubMed links to this paper include Circadian Rhythm, Combat Disorders, Down-Regulation, Human Growth Hormone, Memory Disorders, Polysomnography and Prognosis.

What This Means in Plain Language

This is a clinical trial of Exogenous HGH, sermorelin & older GHRPs (why they're passed over).

The abstract goes on to report its results in about 5 sentences; this page does not restate them, so read the paper for the findings and their limits.

The publication is from 2011 (Psychoneuroendocrinology), a journal based in England.

More context: the Exogenous HGH, sermorelin & older GHRPs (why they're passed over) compound page, all human trials.