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Plasma zinc concentration responds to short-term zinc supplementation, but not zinc fortification, in young children in Senegal1,2.
Plain-language guide to PMID 21490143 (2011): double-blind randomized controlled trial of Vitamin D, K2, Magnesium and Zinc in 137 children.
Key Facts
- PMID
- 21490143
- Journal
- The American journal of clinical nutrition
- Year
- 2011
- Study type
- Randomized Controlled Trial
- Authors
- Lo NB et al. (7 authors)
- DOI
- 10.3945/ajcn.111.012278
- Registered trial
- NCT00944398
What This Study Did, in Plain Language
What Was Tested
Researchers studied Vitamin D, K2, Magnesium and Zinc in this randomized controlled trial publication.
Simple, low-cost methods are needed to evaluate the effect of zinc-fortification programs.
The objective was to compare the change in plasma zinc concentrations in young children who received zinc from either a liquid supplement or a zinc-fortified complementary food.
Why It Was Studied
Plasma zinc concentration is a useful biomarker of zinc intake from supplementation, but responses to zinc fortification are inconsistent.
Who Took Part
The abstract describes 137 children taking part.
By PubMed's age tags, the people studied were infants, both men and women.
How the Study Was Run
In design terms this was a randomized and double-blind study.
The children were allocated by chance, so the Vitamin D, K2, Magnesium and Zinc group and the comparison group should start out alike.
Blinding on both sides kept the children and researchers unaware of who received Vitamin D, K2, Magnesium and Zinc.
What Was Measured
The subject headings attached to it are Biomarkers, Dietary Supplements, Edible Grain, Food, Fortified, Infant Nutritional Physiological Phenomena, Senegal and Zinc.
What This Means in Plain Language
The paper is a randomized and double-blind study of Vitamin D, K2, Magnesium and Zinc in 137 children.
The abstract goes on to report its results in about 5 sentences; this page does not restate them, so read the paper for the findings and their limits.
The publication is from 2011 (The American journal of clinical nutrition), a journal based in United States.
More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.
Our Notes on the Compound
Vitamin D, K2, Magnesium and Zinc: Magnesium is described as required for AMPK to function.
Related Pages
Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.