Ghrelin but not peptide YY is related to change in body weight and energy availability

What Was Tested

The paper reports a study of Peptide YY and Ghrelin, published as a randomized controlled trial.

The aim of this study was to examine changes in fasting total peptide YY (PYY) and ghrelin in nonobese premenopausal women after an exercise and diet program with and without weight loss.

Who Took Part

By PubMed's age tags, the people studied were teenagers, young adults and adults, women only.

Body composition, energy balance parameters, ghrelin, and PYY were measured before and after a 3-month intervention in nonexercising controls (n = 7) and exercising women who either remained weight stable (n = 5) or lost weight (n = 10).

Subjects were fed a controlled diet.

How the Study Was Run

The researchers set it up as a randomized study.

The participants were allocated by chance, so the Peptide YY group and the comparison group should start out alike.

The methods mention a period of 3 months.

What Was Measured

PubMed files the paper under topics including Adipose Tissue, Diet, Energy Metabolism, Exercise, Ghrelin, Peptide YY and Weight Loss.

What This Means in Plain Language

The paper is a randomized study of Peptide YY and Ghrelin over 3 months.

Its findings take up roughly 7 sentences of the abstract and are left out here on purpose; the source paper is the place to read them.

The publication is from 2011 (Medicine and science in sports and exercise), a journal based in United States.

More context: the Peptide YY compound page and the Ghrelin compound page, all human trials.