[Ovarian stimulation for in vitro fertilization using LHRH agonists: comparison of plasma and intra-follicular hormone profiles using "short" and "long" protocols].

What Was Tested

Researchers studied Buserelin in this clinical trial publication.

Moreover measurements in the plasma and follicular fluid (FF) of E2, P, LH, Delta-4-androstenedione (A), Testosterone (T) and prolactin (PRL) were performed on the day of oocyte retrieval (DO) in 46 women of the group I (111 FF) and 27 of the group II (67 FF).

In the group I, plasma LH always remains below 3 mUl/ml, whatever the type of agonist (Buserelin or DTRP6-LHRH) and the type of stimulation (HMG or FSH) are used.

Who Took Part

The abstract describes 46 women taking part.

The age groups tagged for this paper are adults, women only.

How the Study Was Run

Plasmatic estradiol (E2), progesterone (P) and LH were measured during the follicular phase of 343 cycles induced for in vitro fertilization (IVF) using a LHRH agonist in a "long protocol" (Group I) and 76 cycles in a "short protocol" (Group II).

What Was Measured

Moreover measurements in the plasma and follicular fluid (FF) of E2, P, LH, Delta-4-androstenedione (A), Testosterone (T) and prolactin (PRL) were performed on the day of oocyte retrieval (DO) in 46 women of the group I (111 FF) and 27 of the group II (67 FF).

The subject headings attached to it are Androstenedione, Buserelin, Clinical Protocols, Estradiol, Fertilization in Vitro, Follicular Fluid and Gonadotropin-Releasing Hormone.

What This Means in Plain Language

This is a clinical trial of Buserelin in 46 women.

The publication is from 1990 (Journal de gynecologie, obstetrique et biologie de la reproduction), a journal based in France.

More context: all human trials.