Impact of a resistant dextrin with a prolonged oxidation pattern on day-long ghrelin profile

What Was Tested

Researchers studied Ghrelin in this randomized controlled trial publication.

The effects of a new resistant dextrin ingested at breakfast on day-long metabolic parameters and ghrelin profile at subsequent lunch were investigated.

Who Took Part

According to the abstract, 12 men were involved.

By PubMed's age tags, the people studied were adults, men only.

Oxidation and fermentation patterns were assessed by simultaneous (13)CO(2)/H(2) breath testing.

How the Study Was Run

The researchers set it up as a randomized, single-blind and crossover study.

Because people in this Ghrelin study were split into groups at random, differences between the groups are less likely to reflect who happened to join each one.

In this single-blind Ghrelin study one party knew the assignments and the other did not.

In the crossover set-up each of the men took both Ghrelin and the comparison in turn, acting as their own control.

Both products (RD and Malto) were derived from corn naturally rich in (13)C to follow their metabolic fate (by using stable isotope analysis).

The appearance of exogenous (13)C-glucose in plasma, glycemia, insulinemia, nonesterified fatty acids (NEFAs), and ghrelin concentrations were measured for 10 hours following breakfast ingestion.

What Was Measured

Topics PubMed links to this paper include Blood Glucose, Breath Tests, Carbon Dioxide, Carbon Isotopes, Dextrins, Dietary Carbohydrates and Fatty Acids, Nonesterified.

What This Means in Plain Language

The paper is a randomized, single-blind and crossover study of Ghrelin in 12 men.

With fewer than 40 people, it is a small study, so it is better read as an early signal for further research than as a settled answer.

The abstract goes on to report its results in about 5 sentences; this page does not restate them, so read the paper for the findings and their limits.

The publication is from 2011 (Journal of the American College of Nutrition), a journal based in United States.

More context: the Ghrelin compound page, all human trials.