Type of dietary fat is associated with the 25-hydroxyvitamin D3 increment in response to vitamin D supplementation.

What Was Tested

This randomized controlled trial looks at Vitamin D, K2, Magnesium and Zinc.

Mono- and polyunsaturated fats may have opposing effects on vitamin D absorption.

Who Took Part

The study group was 152 men.

The age groups tagged for this paper are older adults and people over 80, both men and women.

How the Study Was Run

The researchers set it up as a randomized, double-blind and placebo-controlled study.

Random assignment meant chance, not the researchers, decided who got Vitamin D, K2, Magnesium and Zinc and who got the comparison, which limits bias.

Neither the men nor the staff measuring them knew who was on Vitamin D, K2, Magnesium and Zinc, so expectations could not easily colour the readings.

Some men received a placebo instead of Vitamin D, K2, Magnesium and Zinc, giving a reference point.

Intakes of monounsaturated fatty acids (MUFA), polyunsaturated fatty acids (PUFA), and saturated fatty acids (SFA) were estimated by food frequency questionnaire.

What Was Measured

Topics PubMed links to this paper include Calcifediol, Calcium, Dietary Fats, Dietary Supplements, Energy Intake, Energy Metabolism and Fatty Acids, Monounsaturated.

What This Means in Plain Language

The paper is a randomized, double-blind and placebo-controlled study of Vitamin D, K2, Magnesium and Zinc in 152 men.

Results are reported in around 5 sentences of the abstract; we leave them to the paper itself rather than summarise them.

The publication is from 2011 (The Journal of clinical endocrinology and metabolism), a journal based in United States.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.