Zinc absorption and zinc status are reduced after Roux-en-Y gastric bypass: a randomized study using 2 supplements.

What Was Tested

The paper reports a study of Vitamin D, K2, Magnesium and Zinc, published as a randomized controlled trial.

The objective was to evaluate the effects of Roux-en-Y gastric bypass (RYGBP) on zinc status and zinc absorption at different stages after surgery.

The researchers also hypothesized that zinc absorption would be lower after surgery.

Why It Was Studied

Micronutrient deficiencies are common in patients undergoing gastric bypass.

The effect of this type of surgery on zinc absorption and zinc status is not well known.

Who Took Part

PubMed indexes the participants as teenagers, young adults, adults and middle-aged adults, women only.

Anthropometric and body-composition variables and dietary and biochemical indexes of zinc status and zinc absorption were determined in 67 severe and morbidly obese women [mean (±SD) age: 36.9 ± 9.8 y; BMI (in kg/m(2)): 45.2 ± 4.7] who underwent RYGBP.

The subjects were randomly assigned to 1 of 2 vitamin-mineral supplementation groups.

How the Study Was Run

In design terms this was a randomized and single-blind study.

The participants were allocated by chance, so the Vitamin D, K2, Magnesium and Zinc group and the comparison group should start out alike.

Only one side, usually the participants, was kept unaware of whether Vitamin D, K2, Magnesium and Zinc was given.

Measurements were made before and 6, 12, and 18 mo after surgery.

Fifty-six subjects completed the 18-mo follow-up.

What Was Measured

The subject headings attached to it are Alkaline Phosphatase, Anthropometry, Body Composition, Body Mass Index, Deficiency Diseases, Dietary Supplements and Erythrocyte Membrane.

What This Means in Plain Language

The paper is a randomized and single-blind study of Vitamin D, K2, Magnesium and Zinc.

Its findings take up roughly 5 sentences of the abstract and are left out here on purpose; the source paper is the place to read them.

The publication is from 2011 (The American journal of clinical nutrition), a journal based in United States.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.