Effects of liandou qingmai recipe (see text) on endothelin-1, nitric oxide, interleukin-6 and interleukin-10 levels in patients with coronary heart disease

What Was Tested

This randomized controlled trial paper looks at Endothelin-1.

To observe effects of Liandou Qingmai Recipe (see text) on endothelin-1 (ET-1), nitric oxide (NO), interleukin-6 (IL-6) and IL-10 levels in patients with coronary heart disease.

Who Took Part

The abstract describes 10 patients taking part.

By PubMed's age tags, the people studied were middle-aged adults, older adults and people over 80, both men and women.

Total 101 cases with coronary heart disease were randomly divided into a treatment group (n = 45) treated by Liandou Qingmai Recipe and a standard treatment group (control group, n = 56), with a normal group of 16 health persons set up.

Changes of ET-1, NO, IL-6 and IL-10 levels were measured before treatment and after treatment for two weeks.

How the Study Was Run

In design terms this was a randomized study.

Random assignment meant chance, not the researchers, decided who got Endothelin-1 and who got the comparison, which limits bias.

The timeline in the abstract includes two weeks.

And the data were analyzed by SPSS 16.0 statistic software.

What Was Measured

PubMed files the paper under topics including Coronary Disease, Drugs, Chinese Herbal, Endothelin-1, Interleukin-10, Interleukin-6 and Nitric Oxide.

What This Means in Plain Language

The paper is a randomized study of Endothelin-1 in 10 patients over two weeks.

With fewer than 40 people, it is a small study, so it is better read as an early signal for further research than as a settled answer.

Its findings take up roughly 2 sentences of the abstract and are left out here on purpose; the source paper is the place to read them.

The publication is from 2011 (Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan), a journal based in China.

More context: the Endothelin-1 compound page, all human trials.