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Growth hormone treatment in non-growth hormone-deficient children: effects of stopping treatment.
Plain-language guide to PMID 2206005 (1990): double-blind randomized controlled trial of Exogenous HGH, sermorelin & older GHRPs (why they're passed over) in 73 boys.
Key Facts
- PMID
- 2206005
- Journal
- Acta paediatrica Scandinavica. Supplement
- Year
- 1990
- Study type
- Randomized Controlled Trial
- Authors
- Ackland FM et al. (6 authors)
- DOI
- 10.1111/j.1651-2227.1990.tb11595.x
What This Study Did, in Plain Language
What Was Tested
Researchers studied Exogenous HGH, sermorelin & older GHRPs (why they're passed over) in this randomized controlled trial publication.
The mean average GH level was 7.1 mU/l and the mean sum of pulse amplitudes 80.4 mU/l.
No relationship was found between age, height or height velocity and any of the parameters of GH secretion.
Who Took Part
The abstract describes 73 boys taking part.
PubMed indexes the participants as young children, children and teenagers, both men and women.
Overnight physiological growth hormone (GH) secretion was evaluated in 95 short, prepubertal children (73 boys, 22 girls).
The group was randomized to receive placebo, GH or remain under observation for the first 6 months and then all patients received GH treatment for a further 6 months.
How the Study Was Run
The design is described as randomized, double-blind and placebo-controlled.
Because people in this Exogenous HGH, sermorelin & older GHRPs (why they're passed over) study were split into groups at random, differences between the groups are less likely to reflect who happened to join each one.
Blinding on both sides kept the boys and researchers unaware of who received Exogenous HGH, sermorelin & older GHRPs (why they're passed over).
The comparison arm used a placebo, so changes seen with Exogenous HGH, sermorelin & older GHRPs (why they're passed over) could be set against what happens without it.
What Was Measured
The mean average GH level was 7.1 mU/l and the mean sum of pulse amplitudes 80.4 mU/l.
PubMed files the paper under topics including Body Height, Growth, Growth Hormone and Randomized Controlled Trials as Topic.
What This Means in Plain Language
The paper is a randomized, double-blind and placebo-controlled study of Exogenous HGH, sermorelin & older GHRPs (why they're passed over) in 73 boys.
The publication is from 1990 (Acta paediatrica Scandinavica. Supplement), a journal based in Sweden.
More context: the Exogenous HGH, sermorelin & older GHRPs (why they're passed over) compound page, all human trials.
Our Notes on the Compound
Exogenous HGH, sermorelin & older GHRPs (why they're passed over): Constant levels suppress the body's own GHRH, raise somatostatin and dull pituitary response.
Related Pages
Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.