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Sensitivity of the saline load test with and without methylene blue dye in the diagnosis of artificial traumatic knee arthrotomies

Plain-language guide to PMID 22215059 (2012): single-blind randomized controlled trial study of Methylene blue (non-peptide stack partner) in 58 subjects.

Key Facts

PMID
22215059
Journal
Journal of orthopaedic trauma
Year
2012
Study type
Randomized Controlled Trial
Authors
Metzger P et al. (5 authors)
DOI
10.1097/BOT.0b013e3182255167

What This Study Did, in Plain Language

What Was Tested

Researchers studied Methylene blue (non-peptide stack partner) in this randomized controlled trial publication.

See Instructions for Authors for a complete description of levels of evidence.

Who Took Part

The abstract describes 58 subjects taking part.

By PubMed's age tags, the people studied were teenagers, young adults, adults and middle-aged adults, both men and women.

Orthopaedic department, tertiary care medical center.

Subjects scheduled for elective outpatient knee arthroscopy were prospectively enrolled and randomized to a normal saline group or a methylene blue group.

How the Study Was Run

The design is described as randomized and single-blind.

Random assignment meant chance, not the researchers, decided who got Methylene blue (non-peptide stack partner) and who got the comparison, which limits bias.

In this single-blind Methylene blue (non-peptide stack partner) study one party knew the assignments and the other did not.

A total of 58 subjects were enrolled (methylene blue 29, normal saline 29).

What Was Measured

See Instructions for Authors for a complete description of levels of evidence.

The subject headings attached to it are Ambulatory Surgical Procedures, Arthroscopy, Joint Diseases, Knee Joint, Methylene Blue and Range of Motion, Articular.

What This Means in Plain Language

The paper is a randomized and single-blind study of Methylene blue (non-peptide stack partner) in 58 subjects.

Its findings take up roughly 6 sentences of the abstract and are left out here on purpose; the source paper is the place to read them.

The publication is from 2012 (Journal of orthopaedic trauma), a journal based in United States.

More context: the Methylene blue (non-peptide stack partner) compound page, all human trials.

Our Notes on the Compound

Methylene blue (non-peptide stack partner): Described as an electron cycler, not just a dye.

Related Pages

Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.