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Analgesic control and functional outcome after knee arthroscopy: results of a randomized double-blinded trial comparing a hyaluronic acid supplement with bupivacaine.

Plain-language guide to PMID 22266741 (2012): double-blind randomized controlled trial of Bupivacaine and Hyaluronic Acid in 98 patients.

Key Facts

PMID
22266741
Journal
Clinical journal of sport medicine : official journal of the Canadian Academy of Sport Medicine
Year
2012
Study type
Randomized Controlled Trial
Authors
Baker JF et al. (5 authors)
DOI
10.1097/JSM.0b013e318240e123

What This Study Did, in Plain Language

What Was Tested

Researchers studied Bupivacaine and Hyaluronic Acid in this randomized controlled trial publication.

Hyaluronic acid (HA) is a naturally occurring substance within normal synovial joints.

Why It Was Studied

Routine use of HA at the time of knee arthroscopy cannot be recommended.

Who Took Part

The study group was 98 patients.

By PubMed's age tags, the people studied were teenagers, young adults, adults, middle-aged adults, older adults and people over 80, both men and women.

One hundred ten patients presenting for routine arthroscopic procedures were invited to participate in the study.

How the Study Was Run

The design is described as randomized and double-blind.

Because people in this Bupivacaine study were split into groups at random, differences between the groups are less likely to reflect who happened to join each one.

Blinding on both sides kept the patients and researchers unaware of who received Bupivacaine.

What Was Measured

The subject headings attached to it are Anesthetics, Local, Arthroscopy, Bupivacaine, Hyaluronic Acid, Injections, Intra-Articular, Knee Joint and Pain Measurement.

What This Means in Plain Language

The paper is a randomized and double-blind study of Bupivacaine and Hyaluronic Acid in 98 patients.

Its findings take up roughly 5 sentences of the abstract and are left out here on purpose; the source paper is the place to read them.

The publication is from 2012 (Clinical journal of sport medicine : official journal of the Canadian Academy of Sport Medicine), a journal based in United States.

More context: all human trials.

Related Pages

Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.