Short reaction of C-peptide, glucagon-like peptide-1, ghrelin and endomorphin-1 for different style diet in type 2 diabetic patients

What Was Tested

Researchers studied Ghrelin in this clinical trial publication.

The aim of this study was to explore the fast response of C-peptide, glucagon-like peptide-1 (GLP-1), ghrelin and endomorphin-1 (EM-1) to the eastern and western style meals in patients with type 2 diabetes mellitus.

Why It Was Studied

Food composition and style is changing dramatically now, which causes inappropriate secretion of hormones from brain, gastrointestinal and endo-pancreas, may be related to unbalance of glucose in blood.

Who Took Part

The study group was 57 patients.

By PubMed's age tags, the people studied were middle-aged adults and older adults, both men and women.

The study enrolled 57 patients with type 2 diabetes (20 men and 37 women, mean age (67.05 ± 8.26) years).

How the Study Was Run

Eastern style meal (meal A) and western style meal (meal B) were designed to produce the fullness effect.

C-peptide, GLP-1, ghrelin and EM-1 were assessed before (0 hour) and after (2 hours) each diet.

What Was Measured

Food composition and style is changing dramatically now, which causes inappropriate secretion of hormones from brain, gastrointestinal and endo-pancreas, may be related to unbalance of glucose in blood.

PubMed files the paper under topics including C-Peptide, Diabetes Mellitus, Type 2, Diet, Fasting, Ghrelin, Glucagon-Like Peptide 1 and Oligopeptides.

What This Means in Plain Language

This is a clinical trial of Ghrelin in 57 patients.

The abstract goes on to report its results in about 5 sentences; this page does not restate them, so read the paper for the findings and their limits.

The publication is from 2011 (Chinese medical journal), a journal based in China.

More context: the Ghrelin compound page, all human trials.