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Head circumference in untreated and IGF-I treated patients with Laron syndrome: comparison with untreated and hGH-treated children with isolated growth hormone deficiency.

Plain-language guide to PMID 22414926 (2012): review of Exogenous HGH, sermorelin & older GHRPs (why they're passed over).

Key Facts

PMID
22414926
Journal
Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society
Year
2012
Study type
Review
Authors
Laron Z et al. (3 authors)
DOI
10.1016/j.ghir.2012.02.005

What This Paper Covers, in Plain Language

What It Covers

Researchers studied Exogenous HGH, sermorelin & older GHRPs (why they're passed over) in this review publication.

To determine the effects of long IGF-I deficiency and treatment on HC in patients with Laron syndrome (LS).

Why It Was Studied

Head circumference (HC) is a simple and practical measure of brain size, development and longitudinal measurements of the HC in childhood are an index of brain growth.

Who the Included Studies Covered

PubMed indexes the participants as young children, children, teenagers, adults and middle-aged adults, both men and women.

How the Review Was Done

HC was expressed as standard deviation (SD) and Ht as SDS.

HC was measured and plotted on Nellhaus charts.

Linear height (Ht) was measured by a Harpenden Stadiometer.

What Was Measured

Head circumference (HC) is a simple and practical measure of brain size, development and longitudinal measurements of the HC in childhood are an index of brain growth.

PubMed files the paper under topics including Brain, Case-Control Studies, Cephalometry, Dwarfism, Pituitary, Growth Hormone, Head and Human Growth Hormone.

What This Means in Plain Language

This is a review of Exogenous HGH, sermorelin & older GHRPs (why they're passed over).

Results are reported in around 4 sentences of the abstract; we leave them to the paper itself rather than summarise them.

The publication is from 2012 (Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society), a journal based in Scotland.

More context: the Exogenous HGH, sermorelin & older GHRPs (why they're passed over) compound page, all human trials.

Our Notes on the Compound

Exogenous HGH, sermorelin & older GHRPs (why they're passed over): Constant levels suppress the body's own GHRH, raise somatostatin and dull pituitary response.

Related Pages

Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.