Addition of cobalamin to iron and folic acid improves hemoglobin rise in nutritional anemia.

What Was Tested

The paper reports a study of Cyanocobalamin (Vitamin B12) in the context of anemia, published as a randomized controlled trial.

Who Took Part

The abstract describes 150 children taking part.

By PubMed's age tags, the people studied were infants and young children, both men and women.

This study included 150 children aged between 0.5-5 y having nutritional anemia.

Serum levels of ferritin were obtained in all cases while levels of cbl and folic acid (FA) were done only in children having macrocytic or dimorphic anemia.

How the Study Was Run

In design terms this was a randomized study.

Because people in this Cyanocobalamin (Vitamin B12) study were split into groups at random, differences between the groups are less likely to reflect who happened to join each one.

Anemia was categorized for severity and red cell morphology.

Children were randomized to receive either iron and FA (Group I) or iron, FA and cbl (Group II).

Response to treatment was assessed at 2, 4 and 8 wk.

What Was Measured

PubMed files the paper under topics including Anemia, Enzyme-Linked Immunosorbent Assay, Folic Acid, Hemoglobins, Infant Nutrition Disorders, Iron and Vitamin B 12.

What This Means in Plain Language

The paper is a randomized study of Cyanocobalamin (Vitamin B12) in 150 children in people with anemia.

Its findings take up roughly 7 sentences of the abstract and are left out here on purpose; the source paper is the place to read them.

The publication is from 2012 (Indian journal of pediatrics), a journal based in India.

More context: the Cyanocobalamin (Vitamin B12) compound page, Anemia research.