← Human Trials & Peer-Reviewed Studies
Growth hormone treatment for sustained pain reduction and improvement in quality of life in severe fibromyalgia.
Plain-language guide to PMID 22465047 (2012): randomized controlled trial of Exogenous HGH, sermorelin & older GHRPs (why they're passed over) in 120 patients.
Key Facts
- PMID
- 22465047
- Journal
- Pain
- Year
- 2012
- Study type
- Randomized Controlled Trial
- Authors
- Cuatrecasas G et al. (20 authors)
- DOI
- 10.1016/j.pain.2012.02.012
- Registered trial
- NCT00933686
What This Study Did, in Plain Language
What Was Tested
The paper reports a study of Exogenous HGH, sermorelin & older GHRPs (why they're passed over), published as a randomized controlled trial.
The placebo arm was switched to GH treatment from month 6 to month 12 (open phase), and a follow-up period after GH discontinuation was performed until month 18.
Standard treatment for fibromyalgia (selective serotonin re-uptake inhibitors, opioids, and amitriptyline) was maintained throughout the study.
Who Took Part
The study group was 120 patients.
PubMed indexes the participants as young adults, adults and middle-aged adults, women only.
How the Study Was Run
The researchers set it up as a randomized, placebo-controlled and multicenter study.
The patients were allocated by chance, so the Exogenous HGH, sermorelin & older GHRPs (why they're passed over) group and the comparison group should start out alike.
A placebo (an inactive look-alike) gave the Exogenous HGH, sermorelin & older GHRPs (why they're passed over) group a baseline to be compared against.
More than one site took part, so the patients came from several places.
What Was Measured
The subject headings attached to it are Fibromyalgia, Growth Hormone, Pain, Pain Measurement and Quality of Life.
What This Means in Plain Language
The paper is a randomized, placebo-controlled and multicenter study of Exogenous HGH, sermorelin & older GHRPs (why they're passed over) in 120 patients.
The publication is from 2012 (Pain), a journal based in United States.
More context: the Exogenous HGH, sermorelin & older GHRPs (why they're passed over) compound page, all human trials.
Our Notes on the Compound
Exogenous HGH, sermorelin & older GHRPs (why they're passed over): Constant levels suppress the body's own GHRH, raise somatostatin and dull pituitary response.
Related Pages
Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.