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The level of serum anti-Müllerian hormone correlates with vitamin D status in men and women but not in boys.

Plain-language guide to PMID 22508713 (2012): placebo-controlled clinical trial of Vitamin D, K2, Magnesium and Zinc.

Key Facts

PMID
22508713
Journal
The Journal of clinical endocrinology and metabolism
Year
2012
Study type
Clinical Trial
Authors
Dennis NA et al. (6 authors)
DOI
10.1210/jc.2012-1213

What This Study Did, in Plain Language

What Was Tested

This clinical trial looks at Vitamin D, K2, Magnesium and Zinc.

The objective of the study was to determine whether serum levels of AMH are related to 25-hydroxyitamin D [25(OH)D)] status.

Why It Was Studied

Anti-Müllerian hormone (AMH) is a gonad-specific hormone, which is extensively used as a marker of gonadal status.

The level of serum AMH has a high variance in similar individuals for reasons that are unknown.

Who Took Part

By PubMed's age tags, the people studied were young children, children, young adults, adults, middle-aged adults, older adults and people over 80, both men and women.

Three cohorts of participants were analyzed; mature men (n = 113), premenopausal women (n = 33), and 5- to 6-yr-old boys (n = 74).

How the Study Was Run

The design is described as placebo-controlled.

A placebo (an inactive look-alike) gave the Vitamin D, K2, Magnesium and Zinc group a baseline to be compared against.

This was a correlative and intervention study.

What Was Measured

The level of serum AMH has a high variance in similar individuals for reasons that are unknown.

The AMH gene promoter contains a vitamin D response element that may cause vitamin D status to influence serum AMH levels.

PubMed files the paper under topics including Age Factors, Aging, Anti-Mullerian Hormone, Cohort Studies, Health Status, Seasons and Sex Characteristics.

What This Means in Plain Language

The paper is a placebo-controlled study of Vitamin D, K2, Magnesium and Zinc.

Its findings take up roughly 7 sentences of the abstract and are left out here on purpose; the source paper is the place to read them.

The publication is from 2012 (The Journal of clinical endocrinology and metabolism), a journal based in United States.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.

Our Notes on the Compound

Vitamin D, K2, Magnesium and Zinc: Magnesium is described as required for AMPK to function.

Related Pages

Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.