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Raynaud's phenomenon and vitamin D.

Plain-language guide to PMID 22580932 (2013): double-blind randomized controlled trial of Vitamin D, K2, Magnesium and Zinc in 53 patients, raynaud's.

Key Facts

PMID
22580932
Journal
Rheumatology international
Year
2013
Study type
Randomized Controlled Trial
Authors
Hélou J et al. (4 authors)
DOI
10.1007/s00296-012-2445-x

What This Study Did, in Plain Language

What Was Tested

The paper reports a study of Vitamin D, K2, Magnesium and Zinc in the context of raynaud's, published as a randomized controlled trial.

To their knowledge, there have not been studies to evaluate the effect of vitamin D supplementation on Raynaud's phenomenon (RP).

Why It Was Studied

In the vitamin D group, baseline average blood vitamin D level was 20.9 ng/mL.

VAS 0, VAS 1, and VAS 2 were 58.33, 48.09, and 36.2, respectively.

Who Took Part

The study group was 53 patients.

The age groups tagged for this paper are adults and middle-aged adults, both men and women.

How the Study Was Run

The design is described as randomized, double-blind and placebo-controlled.

Random assignment meant chance, not the researchers, decided who got Vitamin D, K2, Magnesium and Zinc and who got the comparison, which limits bias.

As a double-blind Vitamin D, K2, Magnesium and Zinc study, the assignments were hidden from both participants and investigators until the end.

A placebo (an inactive look-alike) gave the Vitamin D, K2, Magnesium and Zinc group a baseline to be compared against.

What Was Measured

In the vitamin D group, baseline average blood vitamin D level was 20.9 ng/mL.

At the end of the study, the average blood vitamin D level was 32.9 ng/mL.

Topics PubMed links to this paper include Dietary Supplements, Raynaud Disease and Vitamin D.

What This Means in Plain Language

The paper is a randomized, double-blind and placebo-controlled study of Vitamin D, K2, Magnesium and Zinc in 53 patients in people with raynaud's.

The publication is from 2013 (Rheumatology international), a journal based in Germany.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, Raynaud's research.

Our Notes on the Compound

Vitamin D, K2, Magnesium and Zinc: Magnesium is described as required for AMPK to function.

Related Pages

Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.