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Raynaud's phenomenon and vitamin D.
Plain-language guide to PMID 22580932 (2013): double-blind randomized controlled trial of Vitamin D, K2, Magnesium and Zinc in 53 patients, raynaud's.
Key Facts
- PMID
- 22580932
- Journal
- Rheumatology international
- Year
- 2013
- Study type
- Randomized Controlled Trial
- Authors
- Hélou J et al. (4 authors)
- DOI
- 10.1007/s00296-012-2445-x
What This Study Did, in Plain Language
What Was Tested
The paper reports a study of Vitamin D, K2, Magnesium and Zinc in the context of raynaud's, published as a randomized controlled trial.
To their knowledge, there have not been studies to evaluate the effect of vitamin D supplementation on Raynaud's phenomenon (RP).
Why It Was Studied
In the vitamin D group, baseline average blood vitamin D level was 20.9 ng/mL.
VAS 0, VAS 1, and VAS 2 were 58.33, 48.09, and 36.2, respectively.
Who Took Part
The study group was 53 patients.
The age groups tagged for this paper are adults and middle-aged adults, both men and women.
How the Study Was Run
The design is described as randomized, double-blind and placebo-controlled.
Random assignment meant chance, not the researchers, decided who got Vitamin D, K2, Magnesium and Zinc and who got the comparison, which limits bias.
As a double-blind Vitamin D, K2, Magnesium and Zinc study, the assignments were hidden from both participants and investigators until the end.
A placebo (an inactive look-alike) gave the Vitamin D, K2, Magnesium and Zinc group a baseline to be compared against.
What Was Measured
In the vitamin D group, baseline average blood vitamin D level was 20.9 ng/mL.
At the end of the study, the average blood vitamin D level was 32.9 ng/mL.
Topics PubMed links to this paper include Dietary Supplements, Raynaud Disease and Vitamin D.
What This Means in Plain Language
The paper is a randomized, double-blind and placebo-controlled study of Vitamin D, K2, Magnesium and Zinc in 53 patients in people with raynaud's.
The publication is from 2013 (Rheumatology international), a journal based in Germany.
More context: the Vitamin D, K2, Magnesium and Zinc compound page, Raynaud's research.
Our Notes on the Compound
Vitamin D, K2, Magnesium and Zinc: Magnesium is described as required for AMPK to function.
Related Pages
Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.