Factors predicting vitamin D response variation in non-Hispanic white postmenopausal women.

What Was Tested

Researchers studied Vitamin D, K2, Magnesium and Zinc in this randomized controlled trial publication.

Understanding factors affecting the response variation is important for identifying subjects who are susceptible to vitamin D deficiency or toxicity.

This study aimed to evaluate potential predictors for vitamin D response variation.

Who Took Part

The abstract describes 1063 subjects taking part.

PubMed indexes the participants as middle-aged adults and older adults, women only.

Vitamin D response was computed for these 1063 subjects as the difference in levels of serum 25(OH)D concentration at the end of a 12-month vitamin D treatment compared with baseline.

How the Study Was Run

In design terms this was a randomized and double-blind study.

The subjects were allocated by chance, so the Vitamin D, K2, Magnesium and Zinc group and the comparison group should start out alike.

As a double-blind Vitamin D, K2, Magnesium and Zinc study, the assignments were hidden from both participants and investigators until the end.

Stepwise linear regression was used to identify predictors of vitamin D response variation.

What Was Measured

Topics PubMed links to this paper include Dietary Supplements, Postmenopause, Regression Analysis, Seasons and Vitamin D.

What This Means in Plain Language

The paper is a randomized and double-blind study of Vitamin D, K2, Magnesium and Zinc in 1063 subjects.

With several hundred people or more, it is a fairly large study for this kind of research.

Its findings take up roughly 6 sentences of the abstract and are left out here on purpose; the source paper is the place to read them.

The publication is from 2012 (The Journal of clinical endocrinology and metabolism), a journal based in United States.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.